LOX Rabbit Polyclonal Antibody (CAB7698)
- SKU:
- CAB7698
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LOX Rabbit Polyclonal Antibody |
SKU: | CAB7698 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human LOX (NP_002308.2). |
Sequence: | EFSH YDLL DANT QRRV AEGH KASF CLED TSCD YGYH RRFA CTAH TQGL SPGC YDTY GADI DCQW IDIT DVKP GNYI LKVS VNPS YLVP ESDY TNNV VRCD I |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AAT10; LOX |
Positive Sample: | 293T,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular space. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
Purification Method: | Affinity purification |
Gene ID: | 4015 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |