LONP2 Rabbit Polyclonal Antibody (CAB15909)
- SKU:
- CAB15909
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LONP2 Rabbit Polyclonal Antibody |
SKU: | CAB15909 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LONP2 (NP_113678.2). |
Sequence: | MSSV SPIQ IPSR LPLL LTHE GVLL PGST MRTS VDSA RNLQ LVRS RLLK GTSL QSTI LGVI PNTP DPAS DAQD LPPL HRIG TAAL AVQV VGSN WPKP HYTL LITG LCRF QIVQ VLKE KPYP IAEV EQLD RLEE FPNT CKMR EELG ELSE QFYK YAVQ LVEM LDMS VPAV AKLR RLLD SLPR EALP DILT SIIR TSNK EKLQ ILDA VSLE ERFK MTIP LLVR QIEG LKLL QKTR KPKQ DDDK RVIA IRPI RRIT HISG TLED EDED EDND DIVM LEKK IRTS SMPE QAHK VCVK EIKR LKKM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LONP; PLON; LONPL; PSLON; LONP2 |
Positive Sample: | U-87MG,HeLa,A-375,Mouse kidney,Mouse liver,Mouse lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Peroxisome matrix. |
Calculated MW: | 95kDa |
Observed MW: | 110kDa |
In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 83752 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |