The LOH12CR1 Polyclonal Antibody (PACO10276) is a valuable tool for research involving LOH12CR1, a protein associated with chromosomal instability and tumorigenesis. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting LOH12CR1 in human samples, making it a reliable choice for Western blot applications. By targeting the LOH12CR1 protein, researchers can analyze its expression in various cell types, providing insights into its role in cancer development and progression.LOH12CR1, also known as a tumor suppressor gene, is implicated in maintaining genomic stability and preventing the accumulation of mutations that can lead to cancer. Its dysregulation is linked to chromosomal instability, a hallmark of many cancer types.
By studying LOH12CR1, researchers can uncover new potential targets for cancer therapy and better understand the molecular mechanisms driving tumorigenesis.This antibody is a valuable tool for investigators studying the molecular pathways involved in cancer development and progression. Its ability to specifically detect LOH12CR1 in human samples makes it an essential reagent for research in oncology and genetics. By utilizing this antibody in their studies, researchers can advance our understanding of the mechanisms underlying cancer and potentially identify new strategies for cancer treatment.
loss of heterozygosity, 12, chromosomal region 1;LOH12CR1;LOH1CR12 ;
UniProt Protein Function:
LOH12CR1: Belongs to the LOH12CR1 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 12p12Cellular Component: membraneMolecular Function: protein binding