The LNX1 Polyclonal Antibody (CAB6481) is a valuable tool for researchers studying LNX1, a protein involved in various cellular processes including protein degradation and cell signaling. This antibody, produced in rabbits, is highly specific to human LNX1 and has been validated for use in Western blot applications.LNX1 is known to interact with multiple proteins in the cell, playing a role in regulating pathways related to cell growth, differentiation, and survival. By targeting LNX1, researchers can gain insights into the mechanisms underlying these processes and investigate its potential as a therapeutic target in diseases such as cancer and neurological disorders.
With its high reactivity and specificity, the LNX1 Polyclonal Antibody is an essential tool for studying the function and regulation of LNX1 in various cellular contexts. Its application in research on protein-protein interactions, intracellular signaling, and cellular homeostasis makes it a valuable addition to studies in cell biology and molecular biology.
Product Name:
LNX1 Rabbit Polyclonal Antibody
SKU:
CAB6481
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 501-594 of human LNX1 (NP_001119800.1).
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
84708
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LNX1 Rabbit pAb (CAB6481) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
