The LMO3 Polyclonal Antibody (PAC021903) is a valuable tool for researchers studying the LIM domain only 3 (LMO3) protein, which plays a crucial role in various cellular processes, including development, differentiation, and oncogenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is ideal for use in Western blot applications.LMO3 is a transcription factor that is involved in the regulation of gene expression and has been implicated in the development and progression of various cancers, making it a promising target for cancer research. By targeting LMO3 with this antibody, researchers can detect and analyze the protein in different cell types, providing valuable insights into its function and potential role in disease pathways.
Furthermore, the LMO3 Polyclonal Antibody is a valuable tool for studying the molecular mechanisms underlying LMO3-mediated signaling pathways and its potential as a therapeutic target in cancer treatment. Its high specificity and sensitivity make it a reliable choice for researchers in the fields of oncology, molecular biology, and developmental biology. Unlock the potential of LMO3 research with this high-quality antibody.
Antibody Name:
LMO3 Antibody (PACO21903)
Antibody SKU:
PACO21903
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human LMO3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from COS-7 cells, using LMO3 antibody.
Background:
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.
Synonyms:
LIM domain only protein 3; Neuronal-specific transcription factor DAT1; Rhombotin-3; LMO3; RBTN3
UniProt Protein Function:
LMO3: 3 isoforms of the human protein are produced by alternative splicing
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: cytoplasm
Molecular Function:protein binding; zinc ion binding
Biological Process: positive regulation of fat cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent
NCBI Summary:
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
