LMO3 Antibody (PACO01025)
- SKU:
- PACO01025
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- NHP - Monkey
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LMO3 Antibody (PACO01025)
The LMO3 Antibody (PAC01025) is a valuable tool for researchers studying LIM domain only 3 (LMO3), a transcription factor involved in neuronal development and cancer progression. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.LMO3 plays a critical role in regulating gene expression and cellular differentiation, making it a key target for research in neuroscience and oncology.
Increased expression of LMO3 has been linked to aggressive forms of neuroblastoma and other cancers, highlighting its potential as a therapeutic target.By using the LMO3 Antibody, researchers can better understand the role of LMO3 in disease development and progression, ultimately leading to the development of targeted therapies for cancer and neurological disorders. Its high specificity and sensitivity make it an essential tool for studies focusing on LMO3 and its biological functions.
| Antibody Name: | LMO3 Antibody |
| Antibody SKU: | PACO01025 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat, Monkey |
| Immunogen: | synthesized peptide derived from the C-terminal region of human LMO3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | LMO3; RBTN3; RBTNL2; RHOM3; LIM domain only protein 3; LMO-3; Neuronal-specific transcription factor DAT1; Rhombotin-3 |
| UniProt Protein Function: | LMO3: 3 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12p12.3 Cellular Component: cytoplasm Molecular Function:protein binding; zinc ion binding Biological Process: positive regulation of fat cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| NCBI Summary: | The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q8TAP4 |
| NCBI GenInfo Identifier: | 34098603 |
| NCBI Gene ID: | 55885 |
| NCBI Accession: | Q8TAP4.1 |
| UniProt Secondary Accession: | Q8TAP4,Q58A66, Q58A67, Q8N974, Q9UDD5, B4DG90, B4DH35 |
| UniProt Related Accession: | Q8TAP4 |
| Molecular Weight: | 18,438 Da |
| NCBI Full Name: | LIM domain only protein 3 |
| NCBI Synonym Full Names: | LIM domain only 3 |
| NCBI Official Symbol: | LMO3Â Â |
| NCBI Official Synonym Symbols: | RBTN3; RHOM3; RBTNL2; Rhom-3Â Â |
| NCBI Protein Information: | LIM domain only protein 3 |
| UniProt Protein Name: | LIM domain only protein 3 |
| UniProt Synonym Protein Names: | Neuronal-specific transcription factor DAT1; Rhombotin-3 |
| Protein Family: | LIM domain only protein |
| UniProt Gene Name: | LMO3Â Â |
| UniProt Entry Name: | LMO3_HUMAN |
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