LMNB1 Rabbit Polyclonal Antibody (CAB16910) is a powerful tool for researchers studying the lamin B1 protein. Lamin B1 is a key component of the nuclear lamina, providing structural support to the nucleus and playing a crucial role in nuclear envelope organization. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.By targeting the lamin B1 protein, this antibody allows for the detection and analysis of lamin B1 expression in various cell types. This makes it ideal for studying nuclear structure and function, as well as for investigating diseases related to nuclear envelope defects.
Researchers in fields such as cell biology, genetics, and oncology can utilize this antibody to gain insights into the role of lamin B1 in cellular processes and disease development.Understanding the function of lamin B1 is essential for unraveling its involvement in diseases such as progeria, muscular dystrophy, and certain cancers. By using the LMNB1 Rabbit Polyclonal Antibody, researchers can uncover new insights into the mechanisms underlying these disorders and potentially identify novel therapeutic targets for intervention.
Product Name:
Lamin B1 Rabbit Polyclonal Antibody
SKU:
CAB16910
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1).
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4001
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Lamin B1 Rabbit pAb (CAB16910) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
