The LMBRD1 Polyclonal Antibody (CAB15866) is a vital tool for researchers studying LMBRD1, a key protein involved in cellular metabolism and vitamin B12 transport. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications. By targeting the LMBRD1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it essential for studies in the fields of biochemistry and molecular biology.
LMBRD1 plays a crucial role in the cellular uptake and processing of vitamin B12, a vital nutrient for various biochemical processes in the body. Dysfunction of LMBRD1 has been linked to vitamin B12 deficiencies and related disorders, underscoring the importance of studying this protein in metabolic and nutritional research. By elucidating the function and regulation of LMBRD1, researchers can uncover new insights into vitamin B12 metabolism and potential therapeutic targets for related conditions.
Product Name:
LMBRD1 Rabbit Polyclonal Antibody
SKU:
CAB15866
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human LMBRD1 (NP_060838.3).
This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.
Purification Method:
Affinity purification
Gene ID:
55788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LMBRD1 Rabbit pAb (CAB15866) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
