The LMAN2 Polyclonal Antibody (CAB15394) is a valuable tool for researchers studying LMAN2, a protein involved in protein trafficking and secretion processes within cells. This antibody, produced in rabbits, has high specificity for the human LMAN2 protein and has been validated for use in Western blot applications. By binding to LMAN2, this antibody allows for the detection and analysis of this important protein in various cell types, making it an excellent choice for research in cell biology and molecular biology.
LMAN2 plays a key role in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus, making it essential for proper cellular function. Dysregulation of LMAN2 has been implicated in various diseases, including neurodegenerative disorders and metabolic conditions. By studying the function of LMAN2 using this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.
Product Name:
LMAN2 Rabbit Polyclonal Antibody
SKU:
CAB15394
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-320 of human LMAN2 (NP_006807.1).
Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus membrane, Single-pass membrane protein, Single-pass type I membrane protein.
Calculated MW:
40kDa
Observed MW:
39kDa
This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control.
Purification Method:
Affinity purification
Gene ID:
10960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LMAN2 Rabbit pAb (CAB15394) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
