The LLGL2 Polyclonal Antibody (CAB18366) is a valuable tool for researchers studying LLGL2, a protein involved in cell polarity and cancer progression. This rabbit polyclonal antibody is highly specific for LLGL2 and has been validated for use in various applications, including Western blot and immunofluorescence.LLGL2, also known as Lethal Giant Larvae 2, is a tumor suppressor protein that plays a crucial role in maintaining cell polarity and inhibiting cell proliferation. Dysregulation of LLGL2 has been associated with various types of cancer, making it a promising target for cancer research and therapy development.
By using the LLGL2 Polyclonal Antibody, researchers can detect and analyze LLGL2 expression in different cell types, helping to unravel its functions in cancer biology.Overall, the LLGL2 Polyclonal Antibody is a valuable tool for researchers interested in studying cell polarity, cancer biology, and therapeutic targeting of LLGL2. Its high specificity and sensitivity make it ideal for a wide range of research applications in the field of molecular biology and oncology.
Product Name:
LLGL2 Rabbit Polyclonal Antibody
SKU:
CAB18366
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 921-1020 of human LLGL2 (NP_001026973.1).
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
3993
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using LLGL2 Rabbit pAb (CAB18366) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
