LLGL2 Rabbit Polyclonal Antibody (CAB18366)
- SKU:
- CAB18366
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LLGL2 Rabbit Polyclonal Antibody |
SKU: | CAB18366 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 921-1020 of human LLGL2 (NP_001026973.1). |
Sequence: | FSLS TKWL VEPR CLVD SAET KNHR PGNG AGPK KAPS RARN SGTQ SDGE EKQP GLVM ERAL LSDE RVLK EIQS TLEG DRGS GNWR SHRA AVGC SLSN GGAE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | HGL; LGL2; Hugl-2; LLGL2 |
Positive Sample: | HeLa |
Cellular Localization: | adherens junction, cortical actin cytoskeleton, cytoplasm, cytosol, plasma membrane |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3993 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |