The LLGL2 Polyclonal Antibody (CAB13323) is a valuable tool for researchers studying LLGL2, a key protein involved in cell polarity and tumor suppression. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in various applications, including Western blotting.LLGL2, also known as lethal giant larvae homolog 2, plays a crucial role in maintaining cell polarity and regulating cell division. Its tumor-suppressive function has been implicated in various types of cancer, making it a promising target for cancer research. By binding to the LLGL2 protein, this antibody enables precise detection and analysis in a wide range of cell types, allowing researchers to further explore the mechanisms underlying cell polarity and tumorigenesis.
Studying the role of LLGL2 in cell polarity and tumor suppression is essential for advancing our understanding of cancer development and progression. This antibody provides a reliable tool for investigating the functional significance of LLGL2 in different cellular processes, offering insights that could potentially lead to the development of novel therapeutic strategies for cancer treatment.
Product Name:
LLGL2 Rabbit Polyclonal Antibody
SKU:
CAB13323
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 938-1027 of mouse LLGL2 (NP_663413.2).
Predicted to enable GTPase activator activity; PDZ domain binding activity; and myosin II binding activity. Acts upstream of or within establishment or maintenance of polarity of embryonic epithelium; labyrinthine layer development; and post-embryonic development. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including cardiovascular system; endocrine gland; genitourinary system; gut; and nasal cavity epithelium. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2).
Purification Method:
Affinity purification
Gene ID:
217325
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LLGL2 antibody (CAB13323) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
