The Lipoprotein Lipase Rabbit Monoclonal Antibody (CAB4115) is a valuable tool for researchers studying lipoprotein metabolism and cardiovascular disease. This antibody, produced in rabbits, specifically targets lipoprotein lipase, an enzyme that plays a key role in lipid metabolism by breaking down triglycerides in lipoproteins.Validated for use in various applications including Western blotting and immunohistochemistry, this antibody is highly reactive with human samples, providing reliable and accurate results for studies on the expression and localization of lipoprotein lipase in different tissues and cell types.
Lipoprotein lipase is a critical enzyme involved in the regulation of lipid levels in the bloodstream, making it a potential target for therapeutic interventions aimed at treating dyslipidemia and preventing cardiovascular complications. Research using this antibody can help elucidate the mechanisms underlying lipoprotein metabolism and identify novel strategies for managing lipid disorders and reducing the risk of cardiovascular events.
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
Purification Method:
Affinity purification
Gene ID:
4023
Clone Number:
ARC0904
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Human plasma, using Lipoprotein lipase (LPL) (LPL) Rabbit mAb (CAB4115) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
