The Lipocalin-2 (NGAL) Monoclonal Antibody is a specialized tool for researchers studying Lipocalin-2, a protein known for its role in various physiological and pathological processes. This antibody, produced through monoclonal antibody technology, has high specificity and affinity for Lipocalin-2, ensuring reliable and accurate results in experiments.Lipocalin-2, also called neutrophil gelatinase-associated lipocalin (NGAL), is involved in diverse functions such as iron transport, innate immunity, and cell survival. Its overexpression has been linked to inflammatory diseases, cancer progression, and kidney injury, making it a key target for investigation in multiple research areas.
This monoclonal antibody is suitable for various applications, including Western blotting, immunofluorescence, and immunohistochemistry, providing flexibility for researchers in different experimental setups. By detecting and quantifying Lipocalin-2 expression, this antibody facilitates the study of its functions and therapeutic potential in diseases such as cancer, kidney disorders, and inflammation. For scientists delving into the complexities of Lipocalin-2 biology, this antibody offers a reliable and precise tool for advancing their research goals.
Product Name:
Lipocalin-2/NGAL Monoclonal Antibody
SKU:
CAB23033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthesized peptide derived from human Lipocalin-2/NGAL.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:2000 - 1:6000
Synonyms:
p25; 24p3; MSFI; NGAL; Lipocalin-2/NGAL
Positive Sample:
A-431
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
23kDa
Observed MW:
23kDa
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
Purification Method:
Affinity purification
Gene ID:
3934
Clone Number:
ARC58965
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Lipocalin-2/NGAL antibody (CAB23033) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
