The LIPC Polyclonal Antibody (CAB13508) is a valuable tool for researchers studying the LIPC gene, which encodes for the hepatic lipase enzyme involved in lipid metabolism. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various research applications, including Western blotting.Hepatic lipase plays a crucial role in lipid metabolism, catalyzing the hydrolysis of lipids and promoting the clearance of circulating lipoproteins. Dysregulation of LIPC expression and activity has been associated with dyslipidemia, cardiovascular diseases, and metabolic disorders.
By targeting the LIPC protein, this antibody allows for the detection and analysis of hepatic lipase levels in different cell types and tissues, providing valuable insights into its functions and potential therapeutic implications.Researchers studying lipid metabolism, cardiovascular health, and metabolic disorders will benefit from the use of the LIPC Polyclonal Antibody (CAB13508) in their experiments. Its specificity, sensitivity, and reliability make it a valuable asset for advancing our understanding of hepatic lipase and its role in human health and disease.
Product Name:
LIPC Rabbit Polyclonal Antibody
SKU:
CAB13508
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-499 of human LIPC (NP_000227.2).
Enables phospholipase A1 activity and triglyceride lipase activity. Involved in several processes, including lipid homeostasis; plasma lipoprotein particle remodeling; and triglyceride catabolic process. Located in extracellular space. Implicated in several diseases, including Alzheimer's disease; coronary artery disease; familial combined hyperlipidemia; peripheral vascular disease; and type 2 diabetes mellitus. Biomarker of hyperinsulinism; obesity; and type 1 diabetes mellitus.
Purification Method:
Affinity purification
Gene ID:
3990
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of A549 cells using LIPC antibody (CAB13508). Blue: DAPI for nuclear staining.
