The LIN9 Polyclonal Antibody (CAB17851) is specifically designed for research involving LIN9, a key protein in cell cycle regulation and cancer development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the LIN9 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable tool for immunology and cancer research studies.LIN9 is a pivotal regulatory protein that controls cell division and growth, making it a promising target for exploring cancer progression and potential therapeutic interventions.
Understanding the role of LIN9 in cell cycle regulation is vital for developing strategies to target cancer cells and inhibit tumor growth. This antibody provides researchers with the means to investigate LIN9 function and its implications in cancer biology, paving the way for advancements in cancer treatment and personalized medicine.
Product Name:
LIN9 Rabbit Polyclonal Antibody
SKU:
CAB17851
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2).
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
286826
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using LIN9 Rabbit pAb (CAB17851) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
