The LIN7C Polyclonal Antibody (CAB16544) is a crucial tool for research involving LIN7C, a key protein involved in cell polarity and cell junction formation. This antibody, produced in rabbits, exhibits high reactivity specifically with human samples and has been validated for use in Western blot applications. By binding to the LIN7C protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in cell biology and molecular biology.LIN7C, also known as Human homolog of C.
elegans lin-7, is a critical component of the LIN7 protein family that regulates protein trafficking and localization at cell junctions. Its role in maintaining cellular polarity and adhesion makes it a target of interest in research on cell signaling, development, and disease. By understanding the function of LIN7C, researchers can gain insights into processes such as epithelial cell polarization and neuronal development, offering potential implications for therapeutic strategies targeting related disorders.
Product Name:
LIN7C Rabbit Polyclonal Antibody
SKU:
CAB16544
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human LIN7C (NP_060832.1).
Enables L27 domain binding activity and cytoskeletal protein binding activity. Involved in morphogenesis of an epithelial sheet. Located in cell-cell junction; cytoplasm; and plasma membrane. Part of MPP7-DLG1-LIN7 complex.
Purification Method:
Affinity purification
Gene ID:
55327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LIN7C Rabbit pAb (CAB16544) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
