The LIN7A Polyclonal Antibody (CAB15346) is a valuable tool for researchers studying LIN7A, a protein that plays a key role in cell polarity and cell-cell adhesion. This antibody, produced in rabbits, boasts high reactivity with human samples and is validated for Western blot applications. By specifically binding to the LIN7A protein, researchers can easily detect and analyze LIN7A expression in a variety of cell types.LIN7A is a critical component of the membrane-associated guanylate kinase (MAGUK) family of proteins, which are essential for the proper localization and function of cell junctions and cell signaling complexes.
Dysregulation of LIN7A has been implicated in various diseases, including cancer and neurodevelopmental disorders. Therefore, this antibody is an important tool for studies in cell biology, cancer research, and neuroscience.By understanding the role of LIN7A in cellular functions and disease processes, researchers can develop targeted therapies and interventions to combat diseases associated with LIN7A dysregulation. The LIN7A Polyclonal Antibody is an indispensable asset for researchers seeking to elucidate the intricate functions of LIN7A and its implications in health and disease.
Product Name:
LIN7A Rabbit Polyclonal Antibody
SKU:
CAB15346
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human LIN7A (NP_004655.1).
Sequence:
MLKP SVTS APTA DMAT LTVV QPLT LDRD VARA IELL EKLQ ESGE VPVH KLQS LKKV LQSE FCTA IREV YQYM HETI TVNG CPEF RARA TA
The protein encoded by this gene is involved in generating and maintaining the asymmetric distribution of channels and receptors at the cell membrane. The encoded protein also is required for the localization of some specific channels and can be part of a protein complex that couples synaptic vesicle exocytosis to cell adhesion in the brain.
Purification Method:
Affinity purification
Gene ID:
8825
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LIN7A Rabbit pAb (CAB15346) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
