LIN28 Rabbit Polyclonal Antibody (CAB6034)
- SKU:
- CAB6034
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | LIN28 Rabbit Polyclonal Antibody |
SKU: | CAB6034 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-209 of human LIN28A (NP_078950.1). |
Sequence: | SAKG LESI RVTG PGGV FCIG SERR PKGK SMQK RRSK GDRC YNCG GLDH HAKE CKLP PQPK KCHF CQSI SHMV ASCP LKAQ QGPS AQGK PTYF REEE EEIH SPTL LPEA QN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A; LIN28A |
Positive Sample: | T47D |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 23kDa |
Observed MW: | 28kDa |
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Purification Method: | Affinity purification |
Gene ID: | 79727 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |