The LIMS2 Polyclonal Antibody (CAB13225) is a highly specific antibody designed for research involving LIMS2, a protein involved in cell migration and adhesion. This antibody, generated in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.LIMS2, also known as LIM Zinc Finger Domain Containing 2, plays a crucial role in cell migration and adhesion processes, making it a target of interest in studies related to cancer metastasis, development, and cell signaling. By binding specifically to the LIMS2 protein, this antibody enables accurate detection and analysis in various cell types, providing valuable insights into the mechanisms underlying cell movement and communication.
Research involving LIMS2 is essential for understanding the molecular pathways involved in cell migration and adhesion, with implications for various physiological and pathological processes. The LIMS2 Polyclonal Antibody can serve as a valuable tool for researchers in fields such as cancer biology, developmental biology, and cell biology, facilitating the investigation of LIMS2 function and its potential role in disease progression.
Product Name:
LIMS2 Rabbit Polyclonal Antibody
SKU:
CAB13225
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1).
This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55679
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using LIMS2 Rabbit pAb (CAB13225) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
