The LIMA1 Polyclonal Antibody (CAB11682) is specifically designed for research involving LIMA1, a key protein involved in cytoskeletal dynamics and cell migration. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in western blot applications. By targeting the LIMA1 protein, this antibody enables researchers to detect and analyze its presence in a variety of cell types, making it an excellent tool for studies in cell biology and cancer research.LIMA1, also known as LIM domain and actin binding 1, plays a crucial role in regulating actin dynamics and promoting cell migration, processes that are essential for various physiological and pathological conditions.
Understanding the function of LIMA1 is important for unraveling its roles in cell motility, invasion, and metastasis, particularly in the context of tumor progression. This antibody provides a reliable means to investigate and elucidate the functions of LIMA1, paving the way for potential therapeutic strategies targeting cell migration-related disorders.
Product Name:
LIMA1 Rabbit Polyclonal Antibody
SKU:
CAB11682
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 560-759 of human LIMA1 (NP_057441.1).
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Purification Method:
Affinity purification
Gene ID:
51474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using LIMA1 Rabbit pAb (CAB11682) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
