The LIM2 Polyclonal Antibody (CAB7909) is a valuable tool for researchers studying LIM2, a protein that plays a crucial role in cell adhesion and cytoskeleton organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.LIM2 is known to be involved in the organization of actin filaments and the regulation of cell shape, making it a key player in cell migration and tissue development.
By targeting the LIM2 protein, researchers can gain insights into its functions and mechanisms of action in various cell types, providing valuable information for studies in cell biology and developmental biology.Overall, the LIM2 Polyclonal Antibody is a reliable tool for researchers interested in exploring the role of LIM2 in cellular processes and its potential implications in developmental disorders and diseases related to cell adhesion and cytoskeleton dynamics.
Product Name:
LIM2 Rabbit Polyclonal Antibody
SKU:
CAB7909
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-110 of human LIM2 (NP_085915.2).
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3982
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LIM2 antibody (CAB7909) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
