The LILRB5 Monoclonal Antibody (PAC010253) is a valuable tool for research involving the LILRB5 protein, a member of the leukocyte immunoglobulin-like receptor (LILR) family. This antibody, produced using hybridoma technology, is highly specific for human samples and is suitable for use in various experimental applications, including flow cytometry and immunofluorescence.LILRB5, also known as leukocyte immunoglobulin-like receptor B5, is a cell surface receptor that plays a role in immune regulation and tolerance. It is involved in modulating immune responses and is implicated in the development of autoimmune diseases and cancer.
By targeting LILRB5 with this monoclonal antibody, researchers can investigate its function in different cell types and advance our understanding of its potential as a therapeutic target.The LILRB5 Monoclonal Antibody (PAC010253) provides researchers with a reliable tool for studying the function and expression of the LILRB5 protein in various experimental settings. Its specificity and high affinity make it an essential reagent for studies in immunology, oncology, and autoimmune research.
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5;LILRB5;CD85C;LIR-8;LIR8 ;
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NCBI Summary:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]