Based on the information provided in the URL, the Lilrb5 Polyclonal Antibody (PACO02179) is a valuable tool for researchers studying the Lilrb5 protein, a member of the Leukocyte Immunoglobulin-like Receptor (LILR) family. This antibody is produced in rabbits and has been shown to have high reactivity with human samples, making it suitable for use in various research applications.The Lilrb5 antibody is specifically designed for use in Western blot applications, allowing for the detection and analysis of the Lilrb5 protein in different cell types. The LILR family is known to play a role in immune regulation, particularly in the inhibition of immune responses. By targeting the Lilrb5 protein, researchers can gain insights into its function and potential implications in immunology and cancer research.
Lilrb5, also known as immunoglobulin-like transcript 8 (ILT8), is involved in modulating immune responses and has been linked to diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the role of Lilrb5 in immune regulation is essential for the development of novel therapeutic strategies that target immune function in these disease contexts.In conclusion, the Lilrb5 Polyclonal Antibody (PACO02179) is a valuable research tool for investigating the function of the Lilrb5 protein and its impact on immune regulation, providing valuable insights for studies in immunology and cancer research.
Antibody Name:
LILRB5 Antibody
Antibody SKU:
PACO02179
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human CD85c.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
