The LILRB3 Monoclonal Antibody (PAC027965) is a valuable tool for researchers studying immune regulation and immune responses. LILRB3, also known as leukocyte immunoglobulin-like receptor subfamily B member 3, is a cell surface receptor that plays a role in modulating immune responses. This monoclonal antibody, produced with high specificity and affinity, is ideal for detecting and analyzing LILRB3 protein in human samples. Validated for use in various applications such as Western blot and immunohistochemistry, this antibody allows for detailed exploration of LILRB3 expression and function in different cell types.
LILRB3 has been implicated in various diseases, including cancer and autoimmune disorders, making it a promising target for therapeutic interventions. Understanding the role of LILRB3 in immune regulation is essential for developing novel treatments for these conditions. Researchers in the fields of immunology and cancer research will benefit from using this antibody to further their studies on the mechanisms of immune regulation and immune system dysfunction.
Antibody Name:
Lilrb3 Antibody (PACO27965)
Antibody SKU:
PACO27965
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Leukocyte immunoglobulin-like receptor subfamily B member 3 protein (664-841AA)
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Synonyms:
Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (Cell-surface glycoprotein p91) (Paired immunoglobulin-like receptor B) (PIR-B), Lilrb3, Pirb
UniProt Protein Function:
Pirb: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).Protein type: Membrane protein, integralCellular Component: integral to membrane; membrane; plasma membraneBiological Process: adaptive immune response; B cell homeostasis; B cell mediated immunity; cytokine and chemokine mediated signaling pathway; immune system process; myeloid dendritic cell differentiation
