LILRB2 Rabbit Polyclonal Antibody (CAB10135)
- SKU:
- CAB10135
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | LILRB2 Rabbit Polyclonal Antibody |
SKU: | CAB10135 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human LILRB2/CD85d/ILT4 (NP_005865.3). |
Sequence: | QTGT IPKP TLWA EPDS VITQ GSPV TLSC QGSL EAQE YRLY REKK SASW ITRI RPEL VKNG QFHI PSIT WEHT GRYG CQYY SRAR WSEL SDPL VLVM TGAY PKPT LSAQ PSPV VTSG GRVT LQCE SQVA FGGF ILCK EGED EHPQ CLNS QPHA RGSS RAIF SVGP VSPN RRWS HRCY GYDL NSPY VWSS PSDL LELL VPGV SKKP SLSV QPGP VMAP GES |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10; LILRB2/CD85d/ILT4 |
Positive Sample: | Mouse liver,Mouse kidney,Mouse blood cell,Rat liver,Rat kidney,Rat blood cell |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 65kDa |
Observed MW: | 65kDa |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10288 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |