LILRB1 Rabbit Polyclonal Antibody (CAB12827)
- SKU:
- CAB12827
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | LILRB1 Rabbit Polyclonal Antibody |
SKU: | CAB12827 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-460 of human LILRB1 (Q8NHL6). |
Sequence: | GWMQ TFLL TKEG AADD PWRL RSTY QSQK YQAE FPMG PVTS AHAG TYRC YGSQ SSKP YLLT HPSD PLEL VVSG PSGG PSSP TTGP TSTS GPED QPLT PTGS DPQS GLGR HLG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B; LILRB1 |
Positive Sample: | Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 71kDa |
Observed MW: | 110kDa |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10859 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |