The Liga Antibody (PACO34258) is a highly specific polyclonal antibody designed for research involving Liga, a cell surface molecule implicated in immune regulation. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as Western blotting.Liga is known for its role in immune regulation, specifically inhibiting immune responses. By binding to the Liga protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.
Understanding the function of Liga is crucial for developing therapies that target immune regulation in diseases like cancer, autoimmune disorders, and chronic inflammatory conditions.Overall, the Liga Antibody (PACO34258) is a valuable tool for researchers looking to study the mechanisms of immune regulation and develop novel treatments for immune-related diseases.
Antibody Name:
ligA Antibody (PACO34258)
Antibody SKU:
PACO34258
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli DNA ligase protein (1-671AA)
Western blot. All lanes: DNA ligase antibody at 2µg/ml + DH5a whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 74 kDa. Observed band size: 74 kDa.
Background:
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
Synonyms:
DNA ligase (EC 6.5.1.2) (Polydeoxyribonucleotide synthase [NAD(+)]), ligA, dnaL lig lop pdeC
UniProt Protein Function:
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
UniProt Protein Details:
NCBI Summary:
ligA is an essential gene. [More information is available at EcoGene: EG10534]. LigA is one of two known NAD(+)-dependent DNA ligases, catalyzing the formation of phosphodiester bonds in duplex DNA. [More information is available at EcoCyc: EG10534].
