LIG3 Rabbit Polyclonal Antibody (CAB13507)
- SKU:
- CAB13507
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | LIG3 Rabbit Polyclonal Antibody |
SKU: | CAB13507 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 254-460 of human DNA Ligase III/LIG3 (NP_039269.2). |
Sequence: | CDPR HKDC LLRE FRKL CAMV ADNP SYNT KTQI IQDF LRKG SAGD GFHG DVYL TVKL LLPG VIKT VYNL NDKQ IVKL FSRI FNCN PDDM ARDL EQGD VSET IRVF FEQS KSFP PAAK SLLT IQEV DEFL LRLS KLTK EDEQ QQAL QDIA SRCT ANDL KCII RLIK HDLK MNSG AKHV LDAL DPNA YEAF KASR NLQD VVER VLHN AQE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | LIG2; MTDPS20; LIG3alpha; DNA Ligase III/LIG3 |
Positive Sample: | HeLa,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Mitochondrion, Nucleus. |
Calculated MW: | 113kDa |
Observed MW: | 105kDa |
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 3980 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |