LIG1 Rabbit Polyclonal Antibody (CAB1858)
- SKU:
- CAB1858
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | LIG1 Rabbit Polyclonal Antibody |
SKU: | CAB1858 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 565-790 of human LIG1 (NP_000225.1). |
Sequence: | CEYK YDGQ RAQI HALE GGEV KIFS RNQE DNTG KYPD IISR IPKI KLPS VTSF ILDT EAVA WDRE KKQI QPFQ VLTT RKRK EVDA SEIQ VQVC LYAF DLIY LNGE SLVR EPLS RRRQ LLRE NFVE TEGE FVFA TSLD TKDI EQIA EFLE QSVK DSCE GLMV KTLD VDAT YEIA KRSH NWLK LKKD YLDG VGDT LDLV VIGA YLGR GKRA GRYG GFLL ASYD EDSE EL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | LIGI; IMD96; hLig1; LIG1 |
Positive Sample: | 293T,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 102kDa |
Observed MW: | 140kDa |
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3978 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |