LIFR Rabbit Polyclonal Antibody (CAB12783)
- SKU:
- CAB12783
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | LIFR Rabbit Polyclonal Antibody |
SKU: | CAB12783 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1). |
Sequence: | NPYT LYTF RIRC STET FWKW SKWS NKKQ HLTT EASP SKGP DTWR EWSS DGKN LIIY WKPL PINE ANGK ILSY NVSC SSDE ETQS LSEI PDPQ HKAE IRLD KNDY IISV VAKN SVGS SPPS KIAS MEIP NDDL KIEQ VVGM GKGI LLTW HYDP NMTC DYVI KWCN SSRS EPCL MDWR KVPS NSTE TVIE SDEF RPGI RYNF F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SWS; SJS2; STWS; CD118; LIF-R; LIFR |
Positive Sample: | Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 124kDa |
Observed MW: | 190kDa |
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3977 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |