The LIF Polyclonal Antibody (CAB1288) is a valuable tool for researchers studying leukemia inhibitory factor (LIF), a cytokine known for its role in a variety of cellular processes, including inflammation, hematopoiesis, and immune response regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.LIF is a multifunctional cytokine that is involved in promoting cell growth and differentiation, as well as inhibiting apoptosis. Research on LIF has implicating its involvement in various pathologies, including cancer, inflammation, and neurodegenerative diseases.
By targeting the LIF protein, this antibody allows for the detection and analysis of LIF expression in different cell types, offering insights into its role in disease progression and potential therapeutic interventions.The LIF Polyclonal Antibody is an essential tool for immunology and cancer research, providing researchers with a means to study the complex functions of LIF and its impact on cellular pathways. Its specificity and sensitivity make it a reliable resource for investigating the mechanisms behind LIF signaling and its potential therapeutic applications.
Product Name:
LIF Rabbit Polyclonal Antibody
SKU:
CAB1288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 23-202 of human LIF (NP_002300.1).
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
3976
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of LIF in paraffin-embedded human liver tissue using LIF Rabbit pAb (CAB1288) at a dilution of  1:200 (40x lens). High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
