The LHX6 Polyclonal Antibody (CAB10006) is a valuable tool for researchers studying LIM homeobox 6 (LHX6), a transcription factor involved in neurodevelopment and cell differentiation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in immunofluorescence and immunohistochemistry applications.LHX6 is known for its role in regulating gene expression during embryonic development of the central nervous system, particularly in the formation of GABAergic interneurons. Aberrant expression of LHX6 has been linked to neurological disorders such as epilepsy and schizophrenia, making it a target of interest for understanding brain development and disease.
By targeting the LHX6 protein, this antibody allows researchers to visualize and analyze the expression and localization of LHX6 in various cell types and tissues. Its high specificity and sensitivity make it an essential tool for studies in neuroscience, developmental biology, and neurodevelopmental disorders. Gain insights into the function and regulation of LHX6 with the LHX6 Polyclonal Antibody (CAB10006) from AssayGenie.
Product Name:
LHX6 Polyclonal Antibody
SKU:
CAB24461
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LHX6 (NP_001229263.1).
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
26468
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LHX6 Rabbit pAb (CAB24461) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC):MOLT-4Exposure time: 30s.
_WB_01__46383.1701344904.jpg?c=2&imbypass=on "Western blot analysis of various lysates, using LHX6 Rabbit pAb (CAB24461) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.")
