The LHX6 Polyclonal Antibody (CAB7364) is a valuable tool for researchers studying LIM homeobox 6 (LHX6), a transcription factor that plays a crucial role in the development of the nervous system. This antibody, generated in rabbits, shows high specificity and sensitivity for detecting LHX6 in human samples, making it a reliable choice for Western blot applications.LHX6 is known for its involvement in brain development, particularly in the differentiation and maturation of GABAergic interneurons. Dysregulation of LHX6 has been linked to neurological disorders such as epilepsy and schizophrenia, highlighting its importance in neural development and function.
By targeting LHX6 with this antibody, researchers can investigate its role in neurodevelopmental processes and potentially uncover new insights into neurological disorders.Overall, the LHX6 Polyclonal Antibody is a valuable tool for researchers interested in studying the functions and regulatory mechanisms of LHX6 in the context of neurodevelopment and neurological disorders. Its high specificity and sensitivity make it a reliable choice for experiments aimed at unraveling the complexities of neural development and function.
Product Name:
LHX6 Rabbit Polyclonal Antibody
SKU:
CAB7364
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 143-392 of human LHX6 (NP_055183.2).
This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
26468
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LHX6 Rabbit pAb (CAB7364) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
