The LHX4 Polyclonal Antibody (CAB8072) is a valuable tool for researchers studying the LIM homeobox protein 4 (LHX4), a transcription factor known for its role in pituitary gland development and function. This antibody, also raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the LHX4 protein, this antibody enables researchers to detect and analyze LHX4 in various cell types, making it an essential tool for studies in endocrinology and developmental biology.
LHX4 is a critical regulator of pituitary gland development, controlling the differentiation of hormone-producing cells essential for the body's hormonal balance. Dysregulation of LHX4 has been linked to various endocrine disorders, making it a key target for research into diseases such as pituitary tumors, hormonal deficiencies, and growth disorders. Understanding the function of LHX4 is essential for elucidating the molecular mechanisms underlying these conditions and developing targeted therapeutic interventions.
Product Name:
LHX4 Rabbit Polyclonal Antibody
SKU:
CAB8072
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 121-390 of human LHX4 (NP_203129.1).
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4.
Purification Method:
Affinity purification
Gene ID:
89884
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using LHX4 Rabbit pAb (CAB8072) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
