The LHFPL1 Polyclonal Antibody (PAC037470) is a valuable tool for researchers studying LHFPL1, a protein associated with lipid metabolism and sensory perception. This antibody, derived from rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the LHFPL1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it particularly useful in studies related to metabolism, sensory biology, and lipid signaling pathways.
LHFPL1, also known as lipoma HMGIC fusion partner-like 1, plays a crucial role in lipid metabolism and may be involved in sensory processes such as taste perception. Its significance in lipid homeostasis and sensory physiology makes it a promising target for research into metabolic disorders, sensory perception disorders, and related conditions. Understanding the function of LHFPL1 is key to developing new treatments and interventions for these health issues.
Immunofluorescent analysis of Hela cells using PACO37470 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human liver cancer using PACO37470 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO37470 at dilution of 1:100.
Synonyms:
LHFPL tetraspan subfamily member 1 protein (Lipoma HMGIC fusion partner-like 1 protein), LHFPL1
UniProt Protein Function:
LHFPL1: a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: Xq23
UniProt Protein Details:
NCBI Summary:
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]