LGR5/GPR49 Rabbit Polyclonal Antibody (CAB10545)
- SKU:
- CAB10545
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LGR5/GPR49 Rabbit Polyclonal Antibody |
SKU: | CAB10545 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5/GPR49 (NP_003658.1). |
Sequence: | NPHF KEDL VSLR KQTY VWTR SKHP SLMS INSD DVEK QSCD STQA LVTF TSSS ITYD LPPS SVPS PAYP VTES CHLS SVAF VPCL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:100 - 1:500 |
Synonyms: | FEX; HG38; GPR49; GPR67; GRP49; LGR5/GPR49 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Golgi apparatus, Multi-pass membrane protein, trans-Golgi network membrane. |
Calculated MW: | 100kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8549 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |