The LGR5/GPR49 Rabbit Monoclonal Antibody is a valuable tool for researchers studying the LGR5/GPR49 protein, which is known to play a critical role in stem cell regulation and tissue repair processes. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in a variety of research applications including immunohistochemistry and flow cytometry.The LGR5/GPR49 protein, also known as leucine-rich repeat-containing G protein-coupled receptor 5, is a marker for stem cells in various tissues, including the intestines and hair follicles. Its involvement in regulating cell proliferation and differentiation makes it a target of interest in studies of tissue regeneration and cancer biology.
By using this antibody, researchers can accurately detect and analyze the expression of LGR5/GPR49 in different cell types and tissues, providing valuable insights into its functions and potential therapeutic applications.Overall, the LGR5/GPR49 Rabbit Monoclonal Antibody is a reliable tool for researchers looking to investigate the role of the LGR5/GPR49 protein in stem cell biology, tissue regeneration, and cancer development. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of the molecular mechanisms underlying these processes.
Product Name:
LGR5/GPR49 Rabbit Monoclonal Antibody
SKU:
CAB12327
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-907 of human LGR5/GPR49 (O75473).
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8549
Clone Number:
ARC0321
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LGR5/GPR49 Rabbit mAb (CAB12327) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
