LGI1 Rabbit Polyclonal Antibody (CAB5408)
- SKU:
- CAB5408
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LGI1 Rabbit Polyclonal Antibody |
SKU: | CAB5408 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 301-557 of human LGI1 (NP_005088.1). |
Sequence: | QLFG GSHI YKRD SFAN KFIK IQDI EILK IRKP NDIE TFKI ENNW YFVV ADSS KAGF TTIY KWNG NGFY SHQS LHAW YRDT DVEY LEIV RTPQ TLRT PHLI LSSS SQRP VIYQ WNKA TQLF TNQT DIPN MEDV YAVK HFSV KGDV YICL TRFI GDSK VMKW GGSS FQDI QRMP SRGS MVFQ PLQI NNYQ YAIL GSDY SFTQ VYNW DAEK AKFV KFQE LNVQ APRS FTHV SINK RNFL FASS FKGN TQIY KHVI VDLS A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; LGI1 |
Positive Sample: | U-87MG,HeLa,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Secreted, synapse. |
Calculated MW: | 64kDa |
Observed MW: | 64kDa |
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9211 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |