The LGALS3BP Polyclonal Antibody (CAB6929) is a valuable tool for researchers studying LGALS3BP, a protein involved in various cellular processes, including cell adhesion, migration, and signaling. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications, providing reliable detection and analysis of LGALS3BP in different sample types.LGALS3BP, also known as Mac-2 binding protein, is implicated in cancer progression, metastasis, and immune regulation. Its expression has been linked to tumor growth and invasion, as well as immune cell activation and response.
Research on LGALS3BP is important for understanding its role in cancer development and immunity, potentially leading to the development of novel therapeutic strategies targeting this protein.Overall, the LGALS3BP Polyclonal Antibody is a versatile tool for investigating the function and expression of LGALS3BP in various biological contexts, making it a valuable asset for studies in oncology, immunology, and cell biology.
Product Name:
LGALS3BP Rabbit Polyclonal Antibody
SKU:
CAB6929
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 306-585 of human LGALS3BP (NP_005558.1).
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Purification Method:
Affinity purification
Gene ID:
3959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LGALS3BP antibody (CAB6929) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
