Galectin 3/LGALS3 Rabbit Monoclonal Antibody (CAB11198)
- SKU:
- CAB11198
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | Galectin 3/LGALS3 Rabbit Monoclonal Antibody |
SKU: | CAB11198 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Galectin 3/LGALS3 (P17931). |
Sequence: | MADN FSLH DALS GSGN PNPQ GWPG AWGN QPAG AGGY PGAS YPGA YPGQ APPG AYPG QAPP GAYP GAPG AYPG APAP GVYP GPPS GPGA YPSS GQPS ATGA |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; Galectin 3/LGALS3 |
Positive Sample: | HT-29,A549,MCF7,RAW 264.7,Mouse lung,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Secreted. |
Calculated MW: | 26kDa |
Observed MW: | 28kDa |
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix,the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis,innate immunity,cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 3958 |
Clone Number: | ARC0542 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |