LEPREL1 Rabbit Polyclonal Antibody (CAB8068)
- SKU:
- CAB8068
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LEPREL1 Rabbit Polyclonal Antibody |
SKU: | CAB8068 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human LEPREL1 (NP_060662.2). |
Sequence: | IRYG GRQD ENRV PSGV NVEG AEVH GFSM GKKL SPKI DRDL REGG PLLY ENIT FVYN SEQL NGTQ RVLL DNVL SEEQ CREL HSVA SGIM LVGD GYRG KTSP HTPN EKFE GATV LKAL KSGY EGRV PLKS ARLF YDIS EKAR RIVE SYFM LNST LYFS YTHM VCRT ALSG QQDR RNDL SHPI HADN CLLD PEAN ECWK EPPA YTFR DYSA LLYM NDDF EGGE FIFT EMDA KTVT ASIK PKCG RMIS FSSG GENP HGVK AVTK GKRC AVAL WFTL DPLY RELE RIQA DEVI AILD QEQQ GKHE L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MCVD; MLAT4; LEPREL1 |
Positive Sample: | NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Golgi apparatus. |
Calculated MW: | 81kDa |
Observed MW: | 85kDa |
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55214 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |