The LEMD2 Polyclonal Antibody (CAB18558) is a valuable tool for researchers studying LEMD2, a protein involved in various cellular processes including chromatin organization and gene regulation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting LEMD2 protein levels in human samples, making it suitable for use in Western blot applications.LEMD2, also known as LEM domain-containing protein 2, has been implicated in the regulation of nuclear envelope dynamics and is thought to play a role in the maintenance of genomic stability.
Dysregulation of LEMD2 has been associated with various diseases, including cancer and muscular dystrophy, making it an attractive target for further investigation.By utilizing the LEMD2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of LEMD2 in both normal and disease states, ultimately advancing our understanding of the molecular mechanisms underlying these conditions. This antibody is a valuable tool for studies in cell biology, genetics, and disease research.
Product Name:
LEMD2 Rabbit Polyclonal Antibody
SKU:
CAB18558
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human LEMD2 (NP_851853.1).
This gene encodes a LEM domain-containing transmembrane protein of the inner nuclear membrane. The protein is involved in nuclear structure organization and plays a role in cell signaling and differentiation. Mutations in this gene result in Cataract 46, juvenile-onset. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
221496
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using LEMD2 Rabbit pAb (CAB18558) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
