LEF1 Rabbit Monoclonal Antibody (CAB4473)
- SKU:
- CAB4473
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- LEF-1
- TCF10
- TCF1ALPHA
- TCF7L3
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | LEF1 Rabbit Monoclonal Antibody |
SKU: | CAB4473 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant protein fo a sequence within amino acids 50-150 of human LEF1 (Q9UJU2). |
Sequence: | LADI KSSL VNES EIIP ASNG HEVA RQAQ TSQE PYHD KARE HPDD GKHP DGGL YNKG PSYS SYSG YIMM PNMN NDPY MSNG SLSP PIPR TSNK VPVV QPSH A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF1 |
Positive Sample: | Jurkat,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 30-50kDa |
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 51176 |
Clone Number: | ARC1019 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |