LECT2 Antibody (PACO58809)
- SKU:
- PACO58809
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LECT2 Antibody (PACO58809)
The Lect2 Polyclonal Antibody (PACO58809) is a valuable tool for research involving Lect2, a protein involved in immune regulation and inflammation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.Lect2, also known as Leukocyte Cell-derived Chemotaxin 2, plays a crucial role in the regulation of immune responses and inflammatory processes. Studying Lect2 is important for gaining insights into various diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions.
By targeting Lect2, researchers can better understand the mechanisms underlying these conditions and potentially develop new therapies.The Lect2 Polyclonal Antibody enables detection and analysis of Lect2 protein in a variety of cell types, making it an ideal choice for immunology and cancer research studies. By using this antibody, researchers can further investigate the function and regulation of Lect2, ultimately contributing to advancements in the field of immunology and disease research.
Antibody Name: | LECT2 Antibody (PACO58809) |
Antibody SKU: | PACO58809 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Leukocyte cell-derived chemotaxin-2 protein (24-151AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO58809 diluted at 1:400 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. Does not show metalloendopeptidase activity. |
Synonyms: | Leukocyte cell-derived chemotaxin-2 (LECT-2) (hLECT2), LECT2 |
UniProt Protein Function: | LECT2: Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. Belongs to the LECT2/MIM-1 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted Chromosomal Location of Human Ortholog: 5q31.1 Cellular Component: cytoplasm; extracellular space Molecular Function:identical protein binding Biological Process: chemotaxis; skeletal development |
NCBI Summary: | This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14960 |
NCBI GenInfo Identifier: | 59806345 |
NCBI Gene ID: | 3950 |
NCBI Accession: | NP_002293.2 |
UniProt Secondary Accession: | O14960,O14565, Q52M49, B2RA90, |
UniProt Related Accession: | O14960 |
Molecular Weight: | 16,390 Da |
NCBI Full Name: | leukocyte cell-derived chemotaxin-2 |
NCBI Synonym Full Names: | leukocyte cell derived chemotaxin 2 |
NCBI Official Symbol: | LECT2Â Â |
NCBI Official Synonym Symbols: | chm2; chm-IIÂ Â |
NCBI Protein Information: | leukocyte cell-derived chemotaxin-2 |
UniProt Protein Name: | Leukocyte cell-derived chemotaxin-2 |
Protein Family: | Leukocyte cell-derived chemotaxin |
UniProt Gene Name: | LECT2Â Â |
UniProt Entry Name: | LECT2_HUMAN |
Antibodies | ELISA Kits |
LECT2 Antibody (PACO10225) | Human LECT2 / Leukocyte cell-derived chemotaxin-2 ELISA Kit |
Human Leukocyte cell-derived chemotaxin-2 (LECT2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |