LDOC1 Antibody (PACO16610)
- SKU:
- PACO16610
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
LDOC1 Antibody (PACO16610)
The LDOC1 Polyclonal Antibody (PAC016610) is a valuable tool for researchers studying LDOC1, a protein involved in immune regulation and inflammation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LDOC1 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in immunology and cancer research.
LDOC1, also known as Leucine zipper down-regulated in cancer 1, plays a crucial role in modulating immune responses and inflammation. Its involvement in immune regulation makes it a promising target for research related to cancer, autoimmune diseases, and chronic inflammatory conditions. By understanding the function of LDOC1, researchers can develop new therapies that manipulate immune responses for therapeutic benefit in these diseases.
| Antibody Name: | LDOC1 Antibody (PACO16610) |
| Antibody SKU: | PACO16610 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human LDOC1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16610(LDOC1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor κ B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. |
| Synonyms: | leucine zipper, down-regulated in cancer 1 |
| UniProt Protein Function: | LDOC1: May have an important role in the development and/or progression of some cancers. Belongs to the LDOC1 family.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: Xq27Cellular Component: nucleolus; nucleusMolecular Function: protein bindingBiological Process: negative regulation of cell proliferation |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95751 |
| NCBI GenInfo Identifier: | 6912480 |
| NCBI Gene ID: | 23641 |
| NCBI Accession: | NP_036449 |
| UniProt Secondary Accession: | O95751 |
| UniProt Related Accession: | O95751 |
| Molecular Weight: | 17kDa |
| NCBI Full Name: | protein LDOC1 |
| NCBI Synonym Full Names: | LDOC1 regulator of NFKB signaling |
| NCBI Official Symbol: | LDOC1Â Â |
| NCBI Official Synonym Symbols: | Mar7; RTL7; BCUR1; Mart7; SIRH7Â Â |
| NCBI Protein Information: | protein LDOC1 |
| UniProt Protein Name: | Protein LDOC1 |
| UniProt Synonym Protein Names: | Leucine zipper protein down-regulated in cancer cells |
| Protein Family: | Protein |
| UniProt Gene Name: | LDOC1Â Â |
| UniProt Entry Name: | LDOC1_HUMAN |
| Antibodies |
| LDOC1 Antibody (PACO03733) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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