The LDLRAD1 Antibody (PAC022392) is a polyclonal antibody designed for research involving LDLRAD1, a protein involved in lipid metabolism and cardiovascular health. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry. It specifically binds to the LDLRAD1 protein, allowing for the detection and analysis of this protein in different cell types.LDLRAD1, also known as low-density lipoprotein receptor class A domain-containing protein 1, plays a crucial role in cholesterol metabolism and the regulation of LDL receptor activity.
Dysregulation of LDLRAD1 has been associated with cardiovascular diseases, making it a promising target for research in the field of lipid biology and cardiovascular health. Studying the function of LDLRAD1 can provide valuable insights into the mechanisms underlying lipid metabolism and cardiovascular disorders, paving the way for the development of novel therapeutic strategies.
Antibody Name:
LDLRAD1 Antibody (PACO22392)
Antibody SKU:
PACO22392
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human LDLRAD1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells and HepG2 cells, using LDLRAD1 antibody.
Background:
Belongs to the LDLR family. 3 isoforms of the human protein are produced by alternative splicing.
Synonyms:
Low-density lipoprotein receptor class A domain-containing protein 1; LDLRAD1;
UniProt Protein Function:
LDLRAD1: Belongs to the LDLR family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1p32.3Cellular Component: integral to membrane