LDHB Rabbit Monoclonal Antibody (CAB5131)
- SKU:
- CAB5131
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LDHB Rabbit Monoclonal Antibody |
SKU: | CAB5131 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LDHB (P07195). |
Sequence: | MATL KEKL IAPV AEEE ATVP NNKI TVVG VGQV GMAC AISI LGKS LADE LALV DVLE DKLK GEMM DLQH GSLF LQTP KIVA DKDY SVTA NSKI VVVT AGVR |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281; LDHB |
Positive Sample: | HeLa,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion inner membrane |
Calculated MW: | 37kDa |
Observed MW: | 36kDa |
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Purification Method: | Affinity purification |
Gene ID: | 3945 |
Clone Number: | ARC1217 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |