LDHB Rabbit Polyclonal Antibody (CAB7625)
- SKU:
- CAB7625
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | LDHB Rabbit Polyclonal Antibody |
SKU: | CAB7625 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1). |
Sequence: | MATL KEKL IAPV AEEE ATVP NNKI TVVG VGQV GMAC AISI LGKS LADE LALV DVLE DKLK GEMM DLQH GSLF LQTP KIVA DKDY SVTA NSKI VVVT AGVR QQEG ESRL NLVQ RNVN VFKF IIPQ IVKY SPDC IIIV VSNP VDIL TYVT WKLS GLPK HRVI GSGC NLDS ARFR YLMA EKLG IHPS SCHG WILG EHGD SSVA VWSG VNVA GVSL QELN PEMG TDND SENW KEVH KMVV ESAY EVIK LKGY TNWA IGLS VADL IESM LKNL SRIH PVST MVKG MYGI ENEV FLSL PCIL NARG LTSV INQK LKDD EVAQ LKKS ADTL WDIQ KDLK DL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281; LDHB |
Positive Sample: | HeLa,A-431,Jurkat,A-549,Mouse brain,Mouse kidney,Mouse heart,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Purification Method: | Affinity purification |
Gene ID: | 3945 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |