[KO Validated] LDHB Rabbit Polyclonal Antibody (CAB18096)
- SKU:
- CAB18096
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] LDHB Rabbit Polyclonal Antibody |
SKU: | CAB18096 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1). |
Sequence: | ATLK EKLI APVA EEEA TVPN NKIT VVGV GQVG MACA ISIL GKSL ADEL ALVD VLED KLKG EMMD LQHG SLFL QTPK IVAD KDYS VTAN SKIV VVTA GVRQ QEGE SRLN LVQR NVNV FKFI IPQI VKYS PDCI IIVV SNPV DILT YVTW KLSG LPKH RVIG SGCN LDSA RFRY LMAE KLGI HPSS CHGW ILGE HGDS SVAV WSGV NVAG VSLQ ELNP EMGT DNDS ENWK EVHK MVVE SAYE VIKL KGYT NWAI GLSV ADLI ESML KNLS RIHP VSTM VKGM YGIE NEVF LSLP CILN ARGL TSVI NQKL KDDE VAQL KKSA DTLW DIQK DLKD L |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281; HB |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 36kDa |
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Purification Method: | Affinity purification |
Gene ID: | 3945 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |