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LDHB Monoclonal Antibody [PAT14D7AT] (CPAB0204)

SKU:
CPAB0204
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT14D7AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

LDHB Monoclonal Antibody [PAT14D7AT] (CPAB0204)

The LDHB Polyclonal Antibody (CPAB0204) is designed for research involving LDHB, a key enzyme in the glycolytic pathway. The antibody, raised in rabbits, is highly reactive with human, mouse, and rat samples and is validated for use in various applications including Western blot, immunohistochemistry, and ELISA. It binds specifically to the LDHB protein, enabling detection and analysis in a wide range of cell types and tissues, making it ideal for studies in metabolism, cancer research, and metabolic diseases.LDHB is crucial for lactate production and is often dysregulated in cancer cells, leading to increased glycolysis and tumor growth.

Understanding the role of LDHB in metabolic reprogramming and tumorigenesis is essential for developing targeted therapies for cancer and metabolic disorders. The LDHB Polyclonal Antibody provides researchers with a reliable tool to study the expression and activity of LDHB in various biological contexts, paving the way for advancements in cancer treatment and metabolic disease research.

Product Name:LDHB Antibody
Product Sku:CPAB0204
Size:5μg
Host Species:Mouse
Immunogen:Anti-human LDHB mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LDHB amino acids 1-334 purified from Ecoli.
Clone:PAT14D7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:LDHB antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Lactate dehydrogenase (LDH) is an enzyme(EC1.1.1.27) present in a wide variety of organisms, including plants and animals. A tetrameric enzyme that catalyses the interconversion of pyruvateand lactate with concomitant interconversion of NADH and NAD+. At high concentrations of pyruvate, the enzyme exhibits feedback inhibition and the rate of conversion of pyruvate to lactate is decreased. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
Synonyms:Lactate Dehydrogenase, LDH, Lactate Dehydrogenase B, LDHB.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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